PROGRAM

 

The lectures will be organized in the room G of the Department of Chemistry, Biology and Biotechnology UNIVERSITY of PERUGIA, Via Pascoli. just in front of  one of the most important Roman-era monuments in the city, "The Mosaic of Saint Elisabeth," as it is called, is named after the medieval church that stood above it at the time of its discovery.

 

 

MONDAY, 20 APRIL

 

8:00 – 9:00 Registration

9:00 – 9:30 Opening Ceremony: Prof. Claudio Santi

 

 

PL01 Selected compounds  containing sulfur or selenium as organocatalysts, ionic liquids, ligands and/or oxidation catalysts

Jacek Chrzanowski¹, Dorota Krasowska¹, Stanisls Miroshnicheno², Patrycja Pokora-Sobczak¹, Grazyna Mielniczak¹, Adrian Zajac¹ and Jozef Drabowicz.^1,2

¹Center of Molecular and Macromolecular Studies, Polish Academy of Sciences, ²Jan Dlugosz University in Czestochowa (PL)

IL01 Stereoselective ring expansion of 2-azanorbornan-3-yl methanols: a route to bridged azepanes containing sulfur, selenium and other heteroatoms

Elżbieta Wojaczyńska, Jacek Skarżewski

Department of Organic Chemistry, Faculty of Chemistry, Wroclaw University of Technology (PL)

 

FC01 An efficient cascade reaction to synthesize pyrazino-indole compounds from vinyl selenones

Matilde Sisti, Luca Sancineto, Francesca Marini, Claudio Santi, Luana Bagnoli

Department of Pharmaceutical Sciences, University of Perugia (I)

 

FC02 Design and synthesis of diselenides as innovative anti-HIV agents

Alice Mariotti, Luca Sancineto, Oriana Tabarrini, Claudio Santi

Department of Pharmaceutical Sciences, University of Perugia (I)

 

11:00 – 11:30 Break

 

 

FC03 Benzenseleninic Acid-Promoted Cyclization of Alkenoic Acids Under Flow Conditions: A Facile Stereoselective Approach to β-Hydroxy γ-Butirolactones

Francesca Mangiavacchi, Paolo Filipponi, Bruno Cerra, Serena Mostarda, Claudio Santi and Antimo Gioiello

Department of Pharmaceutical Sciences, University of Perugia (I)

 

FC04 A New Vinyl Selenone-Mediated Domino Access to Spirocyclopropyl Oxindoles: Synthesis and anti-HIV Evaluation

Martina Palomba, Luca Rossi, Luca Sancineto, Luana Bagnoli, Claudio Santi, Oriana Tabarrini, Francesca Marini

Department of Pharmaceutical Sciences, University of Perugia (I)

 

FC05  N-substituted 1,2-benzisoselenazol-3(2H)-ones – synthesis and activity

Agata Pacuła, Jacek Ścianowski

Department of Organic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Torun (PL)

 

IL02 Enhancing the chain-breaking antioxidant activity of phenols by ortho-alkylthio substituents

Riccardo Amorati,¹ Caterina Viglianisi,² Stefano Menichetti²

¹Department of Chemistry «G. Ciamician», University of Bologna (I), ²Department of Chemistry ”U. Schiff”, University of Florence (I).

 

 

12:40 – 15:15 Break

 

 

IL03 Oxidation Properties of I₂-Adducts of Thione Containing Ligands

Vito Lippolis

Inorganic and Analitical Chemistry Department, University of Cagliari (I)

 

FC06 Synthesis of new heterogeneous catalysts based on zirconium and selenium and their application in green chemistry

Jawad Mahmoodi,¹ R. Vivani,¹F. Costantino,² M. Taddei,² L. Sancineto,¹ C. Santi.¹

¹Department of Pharmaceutical Sciences,²Department of Chemistry, Biology and Biotecnology University of Perugia (I)

 

FC07 Use of Selenium based MOF in heterogeneous catalysis

Francesca Medori, Claudio Santi, Riccardo Vivani, Ferdinando Costantino,  Luca Sancineto

Department of Pharmaceutical Sciences, University of Perugia (I)

 

 

FC08 New silica based selenorganic heterogeneous catalysts

Agata M. Russo, Claudio Santi, Monica Pica, Riccardo Vivani

Department of Pharmaceutical Sciences, University of Perugia (I)

 

IL04 Detailed characterization of noncovalent weak interactions (halogen and chalcogen bonding) through a combined NMR/DFT approach

Gianluca Ciancaleoni

Centro de Ciências Físicas e Matemáticas, Departamento de Química, Universidade Federal de Santa Catarina (BZ)

 

 17:00 – 17:30 Break

 

 

PL02 Oxidative Stress: Roles of Sulfur and Selenium

Helmut Sies

Institute of Biochemistry and Molecular Biology I and Leibniz Research Institute of Environmental Medicine, Heinrich-Heine-University Düsseldorf (DE)

 

20:00 Social Dinner

 

 

 

 

TUESDAY, 21 APRIL

 

 

PL03 Catalysis with Selenium Electrophiles

Thomas Wirth

School of Chemistry, Cardiff University (UK)

 

IL05 Synthesis and evaluation of antioxidant properties of different selenium containing derivatives. A novel approach to resveratrol benzoselenophenes

Antonella Capperucci,¹ Stefano Menichetti,¹ Damiano Tanini,¹ Riccardo Amorati,² Marco d’Ischia,³ Alessandra Napolitano,³ Lucia Panzella³

¹Department of Chemistry “Ugo Shiff”, University of Florence (I), ²Department of Chemistry «G. Ciamician», University of Bologna (I), ³Department of Chemical Sciences, University of Naples (I).

 

FC09 Diselenides and benzisoselenazolones: synthesis and GPx-Like activity

Luca Sancineto,¹ Vanessa do Nascimento,² Antonio L. Braga² and Claudio Santi^{1 1}Department of Pharmaceutical Sciences, University of Perugia, Perugia, (I) ²Universidad Federal de Santa Catarina, Florianopolis, (BS)

 

FC10 Synthesis of selenium analogues of naturally occurring phenylpropanoids

Serena Fiorito, Salvatore Genovese, Vito A Taddeo, Francesco Epifano

Department of Pharmacy, University “G. D’Annunzio” of Chieti-Pescara (I)

 

FC11 Nucleophilic selenium mediated ring opening of THF

Marialaura Scisciani, Luana Bagnoli, Eder J. Lenardao, Francesca Marini, Luca Sancineto, Claudio Santi

Department of Pharmaceutical Sciences, University of Perugia (I)

 

11:00 – 11:30 Break

 

 

FC12 S-Trityl-(R)-cysteine, a Versatile Chiral Selector for Ligand-Exchange Liquid Chromatography Applications

Federica Ianni, Roccaldo Sardella, Benedetto Natalini

Department of Pharmaceutical Sciences, University of Perugia (I)

 

FC13 Hydrotalcite exchanged with carboxyseleninic acid as heterogeneous catalyst

Divine Mouanda, Claudio Santi, Morena Nocchetti, Luca Sancineto, Riccardo Vivani, F. Marmottini

Department of Pharmaceutical Sciences, University of Perugia (I)

FC18 Ultrasound-promoted cleavage of Se-Se bond:  Synthesis of β-hydroxy selenides

BONIFACIO MONTI,¹ LUCA SANCINETO,¹ LUANA BAGNOLI,¹ FRANCESCA MARINI,¹ CLAUDIO SANTI,¹ EDER J. LENARDÃO^1,2

¹Department of Pharmaceutical Sciences, University of Perugia (I), ² Laboratório de Síntese orgânica Limpa – LASOL – CCQFA-UFPel, Pelotas, RS, (BS)

 

IL06 Sulfur-containing chiral compounds from bicyclic monoterpenoid

Mariola  Zielinska –Blajet, Szymon Waleńczak

Department of Organic Chemistry, Faculty of Chemistry, Wroclaw University of Technology (PL)

 

 

PL04 Organic sulfur and selenium species as targets and protective species in inflammatory diseases

Mike Davies

Department of Biomedical Sciences, University of Copenhagen (DK)

 

13:00 – 15:00 Break

 

 

 

IL07 Controlling biofilms with nitroxides

Stefanie-Ann Alexander

School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne (AU)

 

FC14 Hormetic diselenides reveal the existence of a glutathione S-transferase P-dependent control of the Nrf2 activation response.

Desiree Bartolini, Jada Commodi, Marta Piroddi, Loredana Incipini, Luca Sancineto, Claudio Santi, Francesco Galli.

Department of Pharmaceutical Sciences, University of Perugia (I)

 

FC15 Design and Synthesis of ITE derivatives

Daniela Dolciami, Luana Bagnoli, Antonio Macchiarulo

Department of Pharmaceutical Sciences, University of Perugia (I)

FC16 Can Se biofortification increase the nutraceutical and antioxidant properties of extra virgin olive oil (EVOO)?

Roberto D’Amato,¹ Daniela Businelli,¹ Primo Proietti,¹ Maurizio Servili,¹ Luca Sancineto,² Claudio Santi²

¹Department of agricultural, food and environmental sciences, University of Perugia (I),²Department of Pharmaceutical Sciences, University of Perugia (I)

 

FC17 Organochalcogens in the Plants

Hanane Achibat,¹ Mostafa Khouili,¹ KhAlid Rhazri,¹ Nohad Alomari²

1 Équipe de Chimie Organique et Organométallique Appliquées Université Sultan Moulay Slimane - Faculté des Sciences et Techniques, Béni Mellal.(Maroc), 2 Dept of Pharm. Chemistry College of Pharmacy, University of Mosul (Iraq)

 

 

16:00 – 16:30 Break

 

IL08 New organoselenium compounds against microbial biofilms

Donatella Pietrella,¹ Stefania De Marco,¹ Miranda Piccioni,¹ Vanessa do Nascimento,² Luca Sancineto,¹ Antonio L Braga² and Claudio Santi¹

¹Department of Pharmaceutical Sciences, University of Perugia, Perugia, (I) ²Universidad Federal de Santa Catarina, Florianopolis, (BS)

 

PL05 Therpeutically-Useful Selenium Heterocycles

Carl H Schiesser

School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne (AU)

 

 

17: 40 – 18:00 Concluding Remarks

 

 

20:00 Social Event - to be confirmed